INTERGARD HEPARIN Grafts
Incorporate biologically active heparin on the fabric of the graft.
INTERGARD Heparin grafts have a coating of heparin applied to the inner layer of the graft fabric. The benefits of using an INTERGARD heparin coated graft was demonstrated in a prospective, randomized clinical trial demonstrated significantly higher patency rates and significantly lower amputation rates compared with PTFE1. INTERGARD Heparin grafts are available in knitted and ultra-thin configurations, offering the advantages of heparin for a variety of vascular procedures.
Made of collagen-coated heparin bonded polyester, INTERGARD Heparin grafts are available in Knitted and UltraThin configurations, offering the advantages of heparin for a variety of vascular procedures.
A unique drug/device combination, INTERGARD Heparin has several advantages:
- Proprietary heparin-bonding process designed to allow the antithrombotic and antiproliferative properties of biologically active heparin to be available locally at the graft surface
- Higher patency rates compared to PTFE1
- Significantly lower amputation rates than PTFE1
- Validated for intended use with rifampicin loading
 Devine C, McCollum C; North West Femoro-Popliteal Trial Participants. Heparin-bonded Dacron or polytetrafluorethylene for femoropopliteal bypass: Five-year results of a prospective randomized multicenter clinical trial. J Vasc Surg. 2004 Nov;40(5):924-931.
- Collagen-coated heparin-bonded polyester graft
- Available in Knitted and UltraThin configurations
- Water permeability: ≤ 5 mL . cm-2. min-1
- Healing: Excellent graft healing and tissue incorporation1
- Handling: Superb handling and host vessel conformability
 Becquemin JP, Riff Y, Kovarsky S, et al. Evaluation of a polyester collagen-coated heparin bonded vascular graft. J Cardiovasc Surg 1997 Feb;38(1):7-14.